All-Time Record: Series tied 7-7 (.500)
2020 record: 6-10
Division Finish: (4th/NFC West)
Head Coach: Kyle Shanahan
Key additions: QB Trey Lance, G Aaron Banks, RB Trey Sermon, DL Samson Ebukam
Notable players: QB Jimmy Garoppolo, TE George Kittle, DL Nick Bosa, LB Fred Warner, T Trent Williams, DL Arik Armstead, DL Dee Ford, CB Dontae Johnson
Key losses: WR Kendrick Bourne, DL Solomon Thomas, CB Ahkello Witherspoon
• The Silver and Black have matched up against the 49ers 14 times, with the series tied 7-7.
• The Raiders and 49ers first matchup was in 1970.