Here is the Oakland Raiders injury report.
| Pos | Player | Injury | Wednesday | Thursday | Friday | Game Status |
| OL | Vadal Alexander | Concussion | Did not part. | Did not part. | Did not part. | Doubtful |
| CB | David Amerson | Foot | Limited | Limited | Limited | Questionable |
| DL | Denico Autry | Hand/Ankle | Limited | Limited | Full | -- |
| TE | Jared Cook | Wrist | Limited | Limited | Full | -- |
| WR | Amari Cooper | Ankle | Limited | Limited | Full | -- |
| DL | Mario Edwards Jr. | Ankle | Limited | Limited | Full | -- |
| DT | Treyvon Hester | Ankle | Did not part. | Did not part. | Did not part. | Out |
| C | Rodney Hudson | Ankle/Illness | Limited | Limited | Full | -- |
| CB | Dexter McDonald | Knee | Limited | Limited | Limited | Questionable |
| DB | Keith McGill II | Knee | Limited | Limited | Full | -- |
| WR | Cordarrelle Patterson | Hip | Limited | Limited | Full | -- |
| T | David Sharpe | Illness | (not listed) | (not listed) | Did not part. | Questionable |
Here is the Los Angeles Chargers injury report.
| Pos | Player | Injury | Wednesday | Thursday | Friday | Game Status |
| TE | Jeff Cumberland | Illness | Did not part. | Full | Full | -- |
| RB | Melvin Gordon | Ankle | Did not part. | Limited | Limited | Questionable |
| S | Adrian Phillips | Ankle | Did not part. | Did not part. | Did not part. | Out |
| DT | Corey Liuget | Knee | Limited | Limited | Limited | Questionable |
| T | Russell Okung | Groin | Limited | Limited | Limited | Questionable |
| LB | Denzel Perryman | Hamstring | Limited | Limited | Limited | Questionable |
| C | Spencer Pulley | Knee | Limited | Full | Full | -- |
| LB | Nick Dzubnar | Illness | Full | Full | Full | -- |
| RB | Austin Ekeler | Hand | Full | Full | Full | -- |
| S | Rayshawn Jenkins | Shoulder | Full | Full | Full | -- |
| TE | Antonio Gates | Illness | (not listed) | Did not part. | Full | -- |
